Serum 25-hydroxy vitamin D levels in essential hypertension

T. Granato, E. Anastasi, V. Viggiani, F. Occhiuzzi, A. Angeloni, R. Gradini, M. Suppa

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Journal of Biological Regulators and Homeostatic Agents ›› 2018, Vol. 32 ›› Issue (6) : 1599-1604.
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Serum 25-hydroxy vitamin D levels in essential hypertension

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Abstract

Vitamin D may have prognostic value in hypertension patients and, in addition to conventional biomarkers, could be a valuable tool for disease management. The aim of this study was to assess the association of vitamin D status in patients with essential hypertension and to evaluate its prognostic utility. Forty-eight consecutive patients (40 Caucasian and 8 Asian) aged between 30 and 80 years (mean 61.5, range 34-84 years), were enrolled in the study. The main exclusion criteria were age less than 18 years, kidney failure, onco-hematologic disease, hypo-hyperparathyroidism, osteoporosis, treatment with bisphosphonate or 25(OH) vitamin D supplementation. Of the 48 patients included in the study, hyperlipidemia was described in 28, diabetes type 2 in 8, and ischemic heart disease in 14. Serum electrolytes, calcium, sodium, and potassium concentrations were within normal range. Low 25(OH) vitamin D levels inversely correlated with essential hypertension values (p less than 0.001) were considered extremely significant. The determination of 25(OH) vitamin D levels in patients with essential hypertension could improve the research for possible underlying conditions, which should be managed meticulously according to current guidelines.

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hypertension / 25(OH) vitamin D / biomarkers / diagnosis

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T. Granato , E. Anastasi , V. Viggiani , F. Occhiuzzi , A. Angeloni , R. Gradini , M. Suppa. Serum 25-hydroxy vitamin D levels in essential hypertension. Journal of Biological Regulators and Homeostatic Agents. 2018, 32(6): 1599-1604

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