Dear Colleagues,

Diabetes Mellitus is one of the most common metabolic diseases in the world. Despite the recent increase in diabetes prevention programs, the prevalence of Type 2 diabetes mellitus is increasing at an alarming rate. Both diabetes mellitus itself and its complications are harmful to patients. In addition, patients with diabetes require more costly health insurance. Both diabetes itself and its complications impose a great burden on healthcare systems. Hence, timely diagnosis and effective treatments are mandatory to prevent serious long-term adverse events related to diabetes mellitus. Effective diagnosis and treatment strategies are based on a better understanding of the pathogenesis of the disease itself and its complications.

Research focusing on the pathogenesis of type 2 diabetes mellitus is encouraged. Moreover, studies on both effective treatment strategies for diabetes and on measures which either detect earlier or fully prevent its complications are needed. Treatment choices with maximum efficacy with minimum side effects are welcome in treatment of diabetes mellitus. Though lifestyle changes including altered diet and exercise patterns are currently established first, most patients require additional measures. Treatments with oral hypoglycemic drugs and parenteral glucagon like peptide-1 analogs or insulin are becoming more common. In recent years, surgical procedures such as sleeve gastrectomy, have been implemented for morbidly obese patients with Type 2 diabetes mellitus. Hypoglycemia and other acute complications of diabetes can be minimized with early diagnosis, effective treatment and increased awareness of patients or caregivers. Chronic complications, such as diabetic nephropathy, neuropathy, retinopathy, foot ulcers and macrovascular complications can be avoided or delayed through careful glycemic control.

Novel approaches to diagnosis, treatment strategies, and prevention and early detection methods of complications are required for effective care of the diabetic population. Therefore, reviews or original research papers which aim to achieve a better understanding of the pathogenesis of Type 2 diabetes and its complications, treatment choices and their efficacy, and prevention, timely diagnosis and management of diabetic complications are invited for this special issue.

Waiting eagerly for you valuable contribution.

Gulali Aktas
Guest Editor

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