Special Issues

Nanomaterials in Biomedicine: Antimicrobial, Anticancer, and Cytotoxicity Research
Editor: Marta Kutwin

Submission Deadline: 31 December 2024 (Status: Open)


Special Issue Editor(s)


Dr. Marta Kutwin      Email   |   Website
Department of Nanobiotechnology, Institute Biology, Warsaw University of Life Sciences, Warsaw, Poland
Interests: nanotechnology; green synthesis; biomaterials; graphene oxide; cancer


Special Issue Information

Dear Colleagues,

Green synthesis of nanomaterials represents a crucial approach for reducing environmental pollution and promoting sustainable practices within the field of nanotechnology. This method is designed to minimize the use of hazardous chemicals and energy-intensive processes while maximizing the use of eco-friendly materials. It is important to note that both the selection of plant-based compounds and the conditions used during synthesis can significantly impact the biocompatibility and efficacy of the resulting nanomaterials. Plant-based compounds not only play a crucial role in reducing metal ions into nanoparticles, but also can increase their biocompatibility.

The combination of green-synthesized nanoparticles and plant-based compounds can lead to synergistic effects, in which the nanoparticles and bioactive compounds work together to achieve enhanced results. For example, nanoparticles can be carriers for plant-based compounds, facilitating their controlled release. Moreover, using plant-based compounds for capping and stabilizing nanoparticles can considerably reduce the toxicity and immunogenicity associated with traditional synthetic chemicals, increasing their suitability for use in medical devices and therapies. Therefore, comprehensive research and testing are necessary to optimize the possible combinations of green-synthesized nanoparticles and plant-based compounds for specific applications.

It is crucial to continue to carry out research on the green synthesis of nanomaterials to promote the adoption of green nanomaterials across various industries to combat environmental pollution.

Dr. Marta Kutwin
Guest Editor


Keywords

nanoparticles; green synthesis; nanocomposites; nanotoxicology


Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://www.biolifesas.org/journalx_brha/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

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  • Review
    Palmiro Poltronieri, Sudipta Joardar
    Journal of Biological Regulators and Homeostatic Agents. 2024, 38(8): 5627-5652. https://doi.org/10.23812/j.biol.regul.homeost.agents.20243808.453
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    Biomolecular condensates (BCs), including membraneless organelles, are basically Ribonucleic acid (RNA)-protein complexes that are emerging as a potential candidate because of its paramount significance in revealing fundamentals of cell biology and pathology including cancer. Aiming to understand its importance, scientists are dealing with it in an interdisciplinary manner—from polymer chemistry to genetics. Over time the mechanism of liquid-liquid phase separation (LLPS) and the model of ‘Stickers and Spacers’ have widened our understanding and broadened our scope of approaches to get insights into these molecular entities. RNA molecules and its specific partner proteins, certain ribonucleoproteins (RNPs), play pivotal roles in different trajectories of BCs, i.e., in localization, compartmentalization, epigenetic regulation, and dynamics. However, several aspects need to be made clearer to tackle human diseases including cancer. In addition to the RNAs, in this review specific aspects of the BCs are presented in the context of neurodegenerative diseases, viral infections and cancer, and their link with stress granules (SG), P bodies, paraspeckles, and host encoded and viral encoded non-coding RNAs, discussing cancer associated proteins, tumour suppressors and repressors, dysregulation of cancer signals, and role of super enhancers. A special focus is reserved to oncolytic viruses and epidemic viruses, through the intervention on stress granule protein partners, virus-formed intracellular condensates, and viral RNAs. The review covers not only the basics of BCs but also encompasses the emerging context of condensate-targeted drug discovery and cancer therapeutics by means of Proteolysis-targeting chimera (PROTAC), Ribonuclease-targeting chimera (RIBOTAC), small molecule inhibitors of protein-RNA interactions, Antisense oligonucleotides (ASO) and compounds targeting non-coding RNA (ncRNA) triple helix, determining RNA degradation.